产品名称
TRI40 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/135644
Human Swissprot No.
Q6P9F5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P9F5/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/195359
Mouse Swissprot No.
Q3UWA4
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UWA4
Rat Gene Link
https://www.uniprot.org/uniprot/365528
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6MFY8
免疫原
Synthesized peptide derived from human TRI40 AA range: 85-135
特异性
This antibody detects endogenous levels of TRI40 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the tripartite motif (TRIM) protein family. The encoded protein may play a role as a negative regulator against inflammation and carcinogenesis in the gastrointestinal tract. Alternatively spliced transcript variants that encode different protein isoforms have been described. [provided by RefSeq, Feb 2014],
组织表达
Highly expressed in normal gastrointestinal epithelia but that is down-regulated in gastrointestinal carcinomas and chronic inflammatory lesions of the gastrointestinal tract.
细胞定位
intracellular,IkappaB kinase complex,
功能
similarity:Belongs to the TRIM/RBCC family.,similarity:Contains 1 B box-type zinc finger.,similarity:Contains 1 RING-type zinc finger.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
