产品名称
T2H2L Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/728340
Human Swissprot No.
Q6P1K8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6P1K8/entry
免疫原
Synthesized peptide derived from human T2H2L AA range: 275-325
特异性
This antibody detects endogenous levels of T2H2L at Human
宿主
Polyclonal, Rabbit,IgG
功能
alternative products:A number of isoforms may be produced. The isoforms may be also produced by incomplete gene duplication,function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II.,function:Component of the core-TFIIH basal transcription factor involved in nucleotide excision repair (NER) of DNA and, when complexed to CAK, in RNA transcription by RNA polymerase II. The N-terminus interacts with and regulates XPD whereas an intact C-terminus is required for a successful escape of RNAP II form the promoter.,similarity:Belongs to the GTF2H2 family.,similarity:Contains 1 VWFA domain.,subunit:One of the six subunits forming the core-TFIIH basal transcription factor. Interacts with XPB, XPD, GTF2H1 and GTF2H3.,tissue specificity:Widely expressed, with higher expression in skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
