产品名称
FBX46 Rabbit Polyclonal Antibody
基因名称
FBXO46 FBX46 FBXO34L
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/23403
Human Swissprot No.
Q6PJ61
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PJ61/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/243867
Mouse Swissprot No.
Q8BG80
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BG80
Rat Gene Link
https://www.uniprot.org/uniprot/292686
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q4KLY2
免疫原
Synthesized peptide derived from human FBX46 AA range: 67-117
特异性
This antibody detects endogenous levels of FBX46 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
Members of the F-box protein family, such as FBXO46, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008],
功能
caution:The region from 1 to 163 was deduced from the genomic sequence and ESTs by similarity to the mouse sequence.,function:Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.,similarity:Contains 1 F-box domain.,subunit:Interacts with SKP1A and CUL1.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
