产品名称
ZN473 Rabbit Polyclonal Antibody
基因名称
ZNF473 KIAA1141 ZFP100
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/25888
Human Swissprot No.
Q8WTR7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8WTR7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/243963
Mouse Swissprot No.
Q8BI67
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BI67
免疫原
Synthesized peptide derived from human ZN473 AA range: 279-329
特异性
This antibody detects endogenous levels of ZN473 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the Krueppel C2H2-type zinc-finger family of proteins. The encoded protein, a component of the U7 snRNP complex, plays a role in histone 3'-end pre-mRNA processing and may be required for cell cycle progression to S phase. Expression level and methylation status of this gene may be correlated with bone mineral density. [provided by RefSeq, Jul 2016],
细胞定位
Nucleus . Stable component of Cajal bodies (CBs). Colocalizes with SMN, coilin and U7 snRNA.
功能
function:Involved in histone pre-mRNA processing, most likely by associating with U7 snRNP and interacting with SLBP/pre-mRNA complex.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 1 KRAB domain.,similarity:Contains 20 C2H2-type zinc fingers.,subunit:Interacts with the SLBP/pre-mRNA complex but not with SLBP alone.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
