产品名称
S23A1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/9963
Human Swissprot No.
Q9UHI7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UHI7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/20522
Mouse Swissprot No.
Q9Z2J0
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9Z2J0
Rat Gene Link
https://www.uniprot.org/uniprot/50621
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WTW7
免疫原
Synthesized peptide derived from human S23A1 AA range: 237-287
特异性
This antibody detects endogenous levels of S23A1 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008],
组织表达
Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
alternative products:Experimental confirmation may be lacking for some isoforms,function:Sodium/ascorbate cotransporter. Mediates electrogenic uptake of vitamin C, with a stoichiometry of 2 Na(+) for each ascorbate.,miscellaneous:Treatment with the protein kinase C stimulator PMA results in a 10-fold decrease in ascorbate accumulation in transfected cells.,PTM:Phosphorylated.,similarity:Belongs to the xanthine/uracil permease family. SLC23A subfamily.,tissue specificity:Highly expressed in adult small intestine, kidney, thymus, ovary, colon, prostate and liver, and in fetal kidney, liver and thymus.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
