产品名称
DGLB Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/221955
Human Swissprot No.
Q8NCG7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q8NCG7/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/231871
Mouse Swissprot No.
Q91WC9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q91WC9
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/P0C1S9
免疫原
Synthesized peptide derived from human DGLB AA range: 616-666
特异性
This antibody detects endogenous levels of DGLB at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
细胞定位
Cell membrane ; Multi-pass membrane protein .
功能
cofactor:Calcium.,enzyme regulation:Inhibited by p-hydroxy-mercuri-benzoate and HgCl(2), but not to PMSF. Also inhibited by RHC80267, a drug that blocks 2-AG formation.,function:Catalyzes the hydrolysis of diacylglycerol (DAG) to 2-arachidonoyl-glycerol (2-AG), the most abundant endocannabinoid in tissues. Required for axonal growth during development and for retrograde synaptic signaling at mature synapses.,similarity:Belongs to the AB hydrolase superfamily. Lipase family.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
