产品名称
SEM4G Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/57715
Human Swissprot No.
Q9NTN9
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NTN9/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/26456
Mouse Swissprot No.
Q9WUH7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9WUH7
免疫原
Synthesized peptide derived from human SEM4G AA range: 387-437
特异性
This antibody detects endogenous levels of SEM4G at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011],
细胞定位
Cell membrane; Single-pass type I membrane protein.
功能
function:May play a role in axon guidance.,similarity:Belongs to the semaphorin family.,similarity:Contains 1 Ig-like C2-type (immunoglobulin-like) domain.,similarity:Contains 1 PSI domain.,similarity:Contains 1 Sema domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
