产品名称
KIZ Rabbit Polyclonal Antibody
基因名称
PLK1S1 C20orf19 KIZ NCRNA00153 HT013
蛋白名称
Centrosomal protein kizuna (Polo-like kinase 1 substrate 1)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q2M2Z5
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q2M2Z5/entry
Mouse Swissprot No.
Q3UXL4
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q3UXL4
免疫原
Synthesized peptide derived from human protein . at AA range: 320-400
特异性
KIZ Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
kizuna centrosomal protein(KIZ) Homo sapiens The protein encoded by this gene localizes to centrosomes, strengthening and stabilizing the pericentriolar region prior to spindle formation. The encoded protein usually remains with the mother centrosome after centrosomal duplication. Sevral transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2013],
细胞定位
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cytoplasm, cytoskeleton, cilium basal body . Localizes to centrosomes throughout the cell cycle. After centrosome duplication, it usually remains associated only with the mother centrosome, containing the older mature centriole and particles surrounding it. During prophase, additional particles accumulate around both separating centrosomes. Does not accumulate at the microtubule minus ends, but instead localizes to the centrosomes and centrosome-surrounding area in a microtubule-independent and dependent manner, respectively. .
功能
microtubule cytoskeleton organization,?cytoskeleton organization,?microtubule-based process,?cell cycle,?cell cycle process,?microtubule organizing center organization,?spindle pole body organization,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
