产品名称
AMPL Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51056
Human Swissprot No.
P28838
Human Swissprot Link
https://www.uniprot.org/uniprotkb/P28838/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/66988
Mouse Swissprot No.
Q9CPY7
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CPY7
Rat Gene Link
https://www.uniprot.org/uniprot/289668
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q68FS4
免疫原
Synthesized peptide derived from human AMPL AA range: 332-382
特异性
This antibody detects endogenous levels of AMPL at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
功能
catalytic activity:Release of an N-terminal amino acid, Xaa-|-Yaa-, in which Xaa is preferably Leu, but may be other amino acids including Pro although not Arg or Lys, and Yaa may be Pro. Amino acid amides and methyl esters are also readily hydrolyzed, but rates on arylamides are exceedingly low.,catalytic activity:Release of N-terminal proline from a peptide.,cofactor:Binds 2 zinc ions per subunit. One zinc ion is tightly bound and essential for enzyme activity, while the second metal coordination site can be occupied by zinc, magnesium or manganese to give enzymes of different activities.,function:Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N-terminal amino acids from various peptides.,similarity:Belongs to the peptidase M17 family.,subunit:Homohexamer.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
