产品名称
NIBAN Rabbit Polyclonal Antibody
基因名称
FAM129A C1orf24 NIBAN GIG39
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/116496
Human Swissprot No.
Q9BZQ8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BZQ8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/63913
Mouse Swissprot No.
Q3UW53
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q3UW53
Rat Gene Link
https://www.uniprot.org/uniprot/63912
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q9ESN0
免疫原
Synthesized peptide derived from human NIBAN AA range: 334-384
特异性
This antibody detects endogenous levels of NIBAN at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the family with sequence similarity 129 protein family. This gene is highly expressed in several cancer cells and may serve as a prognostic marker for certain cancers. The encoded protein may play a role in regulating p53-mediated apoptosis. [provided by RefSeq, Sep 2016],
组织表达
Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney.
细胞定位
Cytoplasm . Membrane ; Lipid-anchor .
功能
function:Regulates phosphorylation of a number of proteins involved in translation regulation including EIF2A, EIF4EBP1 and RPS6KB1. May be involved in the endoplasmic reticulum stress response.,miscellaneous:'Niban' means 'second' in Japanese.,similarity:Belongs to the Niban family.,tissue specificity:Expressed in various types of thyroid tumor such as papillary thyroid carcinomas and oxyphilic thyroid tumors but not in normal thyroid tissue (at protein level). Strongly expressed in heart, skeletal muscle, pancreas, white blood cells and prostate with moderate expression in colon and spleen. Expressed in renal carcinoma cells but not in normal kidney.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
