产品名称
DDX47 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51202
Human Swissprot No.
Q9H0S4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9H0S4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67755
Mouse Swissprot No.
Q9CWX9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9CWX9
免疫原
Synthesized peptide derived from human DDX47 AA range: 86-136
特异性
This antibody detects endogenous levels of DDX47 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the DEAD box protein family. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. The protein encoded by this gene can shuttle between the nucleus and the cytoplasm, and has an RNA-independent ATPase activity. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008],
组织表达
Expressed in skin, lung and breast. Also expressed in the brain.
细胞定位
Nucleus, nucleolus . Localizes in the nucleolar-organizing region during ribosome biogenesis.
功能
similarity:Belongs to the DEAD box helicase family.,similarity:Belongs to the DEAD box helicase family. DDX47/RRP3 subfamily.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
