产品名称
G3ST3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/89792
Human Swissprot No.
Q96A11
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96A11/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/545276
Mouse Swissprot No.
P61315
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/P61315
免疫原
Synthesized peptide derived from human G3ST3 AA range: 191-241
特异性
This antibody detects endogenous levels of G3ST3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate group to the 3' position of galactose in N-acetyllactosamine in both type 2 (Gal-beta-1-4GlcNAc-R) oligosaccharides and core-2-branched O-glycans, but not on type 1 or core-1-branched structures. This gene, which has also been referred to as GAL3ST2, is different from the GAL3ST2 gene located on chromosome 2 that encodes a related enzyme with distinct tissue distribution and substrate specificities, compared to galactose-3-O-sulfotransferase 3. [provided by RefSeq, Jul 2008],
组织表达
Highly expressed in thyroid, brain, kidney, heart and spinal cord.
细胞定位
Golgi apparatus, Golgi stack membrane ; Single-pass type II membrane protein .
功能
cofactor:Magnesium.,function:Transfers a sulfate to position 3 of non-reducing beta-galactosyl residues in N-glycans and core2-branched O-glycans. Has high activity towards Gal-beta-1,4-GlcNAc, Gal-beta-1,4(Fuc-alpha-1,3)GlcNAc and lower activity towards Gal-beta-1,3(Fuc-alpha-1,4)GlcNAc.,online information:GlycoGene database,pathway:Protein modification; carbohydrate sulfation.,similarity:Belongs to the galactose-3-O-sulfotransferase family.,tissue specificity:Highly expressed in thyroid, brain, kidney, heart and spinal cord.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
