产品名称
PHF11 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51131
Human Swissprot No.
Q9UIL8
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9UIL8/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/219131
Mouse Swissprot No.
Q8BVM9
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8BVM9
Rat Gene Link
https://www.uniprot.org/uniprot/361051
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q5I0E2
免疫原
Synthesized peptide derived from human PHF11 AA range: 232-282
特异性
This antibody detects endogenous levels of PHF11 at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],
组织表达
Highly expressed in T and B-cells, as well as natural killer and mature dendritic cells. Expressed at higher levels in Th1 as compared to Th2 cells. Expressed at low levels in all normal tissues tested, including lung, testis, small intestine, breast, liver and placenta.
功能
alternative products:A number of isoforms may be produced,polymorphism:Variation in PHF11 seems to be associated with propensity to atopy and asthma.,similarity:Contains 1 PHD-type zinc finger.,subunit:Interacts with BRCA1.,tissue specificity:Expressed in all normal tissues tested, including lung, testis, small intestine, breast, liver and placenta.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
