产品名称
BORA Rabbit Polyclonal Antibody
蛋白名称
Protein aurora borealis (HsBora)
存储缓冲液
Liquid in PBS containing 50% glycerol, and 0.02% New type preservative N.
Human Swissprot No.
Q6PGQ7
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6PGQ7/entry
Mouse Swissprot No.
Q8BS90
Mouse Swissprot Link
http://www.uniprot.org/uniprot/Q8BS90
Rat Swissprot Link
http://www.uniprot.org/uniprot/O54941Q5M864
免疫原
Synthesized peptide derived from human protein . at AA range: 440-520
特异性
BORA Polyclonal Antibody detects endogenous levels of protein.
稀释度
WB 1:500-2000 ELISA 1:5000-20000
宿主
Polyclonal, Rabbit,IgG
背景介绍
BORA is an activator of the protein kinase Aurora A (AURKA; MIM 603072), which is required for centrosome maturation, spindle assembly, and asymmetric protein localization during mitosis (Hutterer et al., 2006 [PubMed 16890155]).[supplied by OMIM, Mar 2008],
组织表达
Bone marrow,Leiomyosarcoma,Rhabdomyosarcoma,Small intestine,Testis carcinom
细胞定位
cytosol,meiotic spindle,
功能
function:Required for the activation of Aurora-A (AURKA/STK6) at the onset of mitosis.,PTM:Phosphorylated by AURKA/STK6.,similarity:Belongs to the BORA family.,subunit:Interacts with AURKA/STK6.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
