产品名称
NMD3 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/51068
Human Swissprot No.
Q96D46
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q96D46/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/97112
Mouse Swissprot No.
Q99L48
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q99L48
免疫原
Synthesized peptide derived from human NMD3 AA range: 235-285
特异性
This antibody detects endogenous levels of NMD3 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
Ribosomal 40S and 60S subunits associate in the nucleolus and are exported to the cytoplasm. The protein encoded by this gene is involved in the passage of the 60S subunit through the nuclear pore complex and into the cytoplasm. Several transcript variants exist for this gene, but the full-length natures of only two have been described to date. [provided by RefSeq, Feb 2016],
细胞定位
Cytoplasm . Nucleus . Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner. .
功能
function:Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit.,similarity:Belongs to the NMD3 family.,subcellular location:Shuttles between the nucleus/nucleolus and the cytoplasm in a XPO1/CRM1-dependent manner.,subunit:Found in a 60S ribosomal subunit export complex with RAN and XPO1. Interacts with XPO1. Associates with the 60S ribosomal subunit.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
