产品名称
RSLBA Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/387496
Human Swissprot No.
Q6T310
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q6T310/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/68895
Mouse Swissprot No.
Q6IMB1
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IMB1
Rat Gene Link
https://www.uniprot.org/uniprot/304268
Rat Swissprot Link
https://www.uniprot.org/uniprotkb/Q6IMA3
免疫原
Synthesized peptide derived from human RSLBA AA range: 68-118
特异性
This antibody detects endogenous levels of RSLBA at Human/Mouse/Rat
宿主
Polyclonal, Rabbit,IgG
背景介绍
RASL11A is a member of the small GTPase protein family with a high degree of similarity to RAS (see HRAS, MIM 190020) proteins.[supplied by OMIM, Nov 2008],
组织表达
Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells.
细胞定位
Nucleus, nucleolus . Associates with rDNA transcription unit throughout the cell cycle. .
功能
developmental stage:Down-regulated during development of THP-1 monocytes into macrophages.,induction:Down-regulated by TGFB1.,similarity:Belongs to the small GTPase superfamily. Ras family.,tissue specificity:Widely expressed. Down-regulated in prostate tumors compared to normal prostate tissue. High levels found in colon tumor and normal colon tissue followed by small intestine, liver, jejunum, ileum, bladder and aorta. Lowest levels observed in endothelial cells.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
