产品名称
OSB11 Rabbit Polyclonal Antibody
基因名称
OSBPL11 ORP11 OSBP12
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/114885
Human Swissprot No.
Q9BXB4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9BXB4/entry
Mouse Swissprot No.
Q8CI95
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q8CI95
免疫原
Synthesized peptide derived from human OSB11 AA range: 180-230
特异性
This antibody detects endogenous levels of OSB11 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Like most members, the encoded protein contains an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain. [provided by RefSeq, Jul 2008],
组织表达
Present at highest levels in ovary, testis, kidney, liver, stomach, brain, and adipose tissue. Strong expression (at protein level) in epithelial cells of kidney tubules, testicular tubules, caecum, and skin (PubMed:20599956). Present at low levels in subcutaneous and visceral adipose tissue (at protein level)(PubMed:23028956).
细胞定位
Late endosome membrane . Golgi apparatus, trans-Golgi network membrane . Localizes at the Golgi-late endosome interface.
功能
similarity:Belongs to the OSBP family.,similarity:Contains 1 PH domain.,tissue specificity:Widely expressed.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
