产品名称
PAPD1 Rabbit Polyclonal Antibody
存储缓冲液
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% New type preservative N.
Human Gene Link
https://www.uniprot.org/uniprot/55149
Human Swissprot No.
Q9NVV4
Human Swissprot Link
https://www.uniprot.org/uniprotkb/Q9NVV4/entry
Mouse Gene Link
https://www.uniprot.org/uniprot/67440
Mouse Swissprot No.
Q9D0D3
Mouse Swissprot Link
https://www.uniprot.org/uniprotkb/Q9D0D3
免疫原
Synthesized peptide derived from human PAPD1 AA range: 445-495
特异性
This antibody detects endogenous levels of PAPD1 at Human/Mouse
宿主
Polyclonal, Rabbit,IgG
背景介绍
The protein encoded by this gene is a member of the DNA polymerase type-B-like family. This enzyme synthesizes the 3' poly(A) tail of mitochondrial transcripts and plays a role in replication-dependent histone mRNA degradation.[provided by RefSeq, Jan 2011],
组织表达
Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle.
细胞定位
Cytoplasm . Mitochondrion .
功能
catalytic activity:ATP + RNA(n) = diphosphate + RNA(n+1).,function:Polymerase that creates the 3' poly(A) tail of mitochondrial transcripts. Might be responsible for the creation of some UAA stop codons which are not encoded in mtDNA.,similarity:Belongs to the DNA polymerase type-B-like family.,tissue specificity:Ubiquitous, with stronger expression in tissues with high energy requirements: heart, brain, and skeletal muscle.,
纯化
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
